BCAM antibody (AA 32-197)

Catalog No. ABIN7193338

Product Details anti-BCAM Antibody

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Binding Specificity: AA 32-197

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCAM antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: CD239 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD239 (AA: 32-197) expressed in E. Coli.

Clone: 8C4E6

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for BCAM

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Alternative Name: CD239 (BCAM Products)

Synonyms: cd239 antibody, msk19 antibody, MGC81012 antibody, LU antibody, prr2 antibody, zgc:154034 antibody, 1200005K12Rik antibody, B-CAM antibody, Gplu antibody, Lu antibody, AU antibody, CD239 antibody, MSK19 antibody, basal cell adhesion molecule (Lutheran blood group) antibody, basal cell adhesion molecule (Lutheran blood group) L homeolog antibody, basal cell adhesion molecule antibody, bcam antibody, bcam.L antibody, BCAM antibody, Bcam antibody

Background:

Description:

This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Aliases: BCAM, AU, LU, MSK19

Molecular Weight: 67.4kDa

Gene ID: 4059