IL17RA antibody (AA 33-320)

Catalog No. ABIN7193333

Product Details anti-IL17RA Antibody

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Binding Specificity: AA 33-320

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD217 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD217 (AA: 33-320) expressed in E. Coli.

Clone: 6H1B1

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: CD217 (IL17RA Products)

Synonyms: IL17R antibody, CANDF5 antibody, CD217 antibody, CDw217 antibody, IL-17RA antibody, hIL-17R antibody, Il17r antibody, AW538159 antibody, Cdw217 antibody, VDw217 antibody, interleukin 17 receptor A antibody, IL17RA antibody, Il17ra antibody

Background:

Description:

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Aliases: IL17RA, IL17R, IMD51, CANDF5, CDw217, IL-17RA, hIL-17R

Molecular Weight: 96.1kDa

Gene ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome