IL7R antibody (AA 21-239)
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- Target See all IL7R Antibodies
- IL7R (Interleukin 7 Receptor (IL7R))
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Binding Specificity
- AA 21-239
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL7R antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA
- Purpose
- CD127 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD127 (AA: 21-239) expressed in E. Coli.
- Clone
- 3F5D9
- Isotype
- IgG2b
- Top Product
- Discover our top product IL7R Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- IL7R (Interleukin 7 Receptor (IL7R))
- Alternative Name
- CD127 (IL7R Products)
- Synonyms
- IL7R antibody, CD127 antibody, IL-7Ralpha antibody, CDW127 antibody, IL-7R-alpha antibody, IL7RA antibody, ILRA antibody, IL-7RA antibody, interleukin 7 receptor antibody, IL7R antibody, Il7r antibody
- Background
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Description:
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
Aliases: IL7R, ILRA, IL7RA, CDW127, IL-7R-alpha
- Molecular Weight
- 51.6kDa
- Gene ID
- 3575
- UniProt
- P16871
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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