LRP6 antibody (AA 1198-1370)
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- Target See all LRP6 Antibodies
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
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Binding Specificity
- AA 1198-1370
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This LRP6 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- LRP6 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human LRP6 (AA: 1198-1370) expressed in E. Coli.
- Clone
- 1A3F5
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
- Alternative Name
- LRP6 (LRP6 Products)
- Synonyms
- lrp6-A antibody, Xlrp6 antibody, adcad2 antibody, lrp6 antibody, LRP6 antibody, ADCAD2 antibody, C030016K15Rik antibody, Cd antibody, Gw antibody, LDL receptor related protein 6 antibody, LDL receptor related protein 6 L homeolog antibody, LDL receptor related protein 6 S homeolog antibody, low density lipoprotein receptor-related protein 6 antibody, low-density lipoprotein receptor-related protein 6 antibody, LRP6 antibody, lrp6.L antibody, lrp6.S antibody, lrp6 antibody, Lrp6 antibody, LOC590395 antibody
- Background
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Description:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Aliases: ADCAD2, STHAG7
- Molecular Weight
- 180kDa
- Gene ID
- 4040
- UniProt
- O75581
- Pathways
- WNT Signaling, Tube Formation
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