PTPRF antibody (AA 1104-1163)
-
- Target See all PTPRF Antibodies
- PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
-
Binding Specificity
- AA 1104-1163
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This PTPRF antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human PTPRF (AA: extra 1104-1163) expressed in E. coli.
- Clone
- 6D7C7
- Isotype
- IgG1
- Top Product
- Discover our top product PTPRF Primary Antibody
-
-
- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- Restrictions
- For Research Use only
-
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
-
- Target
- PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
- Alternative Name
- PTPRF (PTPRF Products)
- Synonyms
- LAR antibody, AA591035 antibody, LARS antibody, RPTP-LAR antibody, LARFN5C antibody, zf-LAR antibody, protein tyrosine phosphatase, receptor type F antibody, protein tyrosine phosphatase, receptor type, F antibody, protein tyrosine phosphatase, receptor type, f, a antibody, PTPRF antibody, Ptprf antibody, ptprfa antibody
- Background
-
Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Aliases: LAR, BNAH2
- Molecular Weight
- 213 kDa
- Gene ID
- 5792
- Pathways
- EGFR Signaling Pathway
-