Thrombomodulin antibody (AA 297-505)

Catalog No. ABIN7193269

Product Details anti-Thrombomodulin Antibody

Target: Thrombomodulin (THBD)

Binding Specificity: AA 297-505

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD141 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD141 (AA: 297-505) expressed in E. Coli.

Clone: 2C6C3

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: CD141 (THBD Products)

Synonyms: AHUS6 antibody, BDCA3 antibody, CD141 antibody, THPH12 antibody, THRM antibody, TM antibody, AI385582 antibody, THBD antibody, HAST antibody, HAST3 antibody, M-PST antibody, ST1A3/ST1A4 antibody, ST1A5 antibody, STM antibody, TL-PST antibody, thrombomodulin antibody, sulfotransferase family 1A member 3 antibody, THBD antibody, Thbd antibody, SULT1A3 antibody

Background:

Description:

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

Aliases: THBD, TM, THRM, AHUS6, BDCA3, THPH12

Molecular Weight: 60.3kDa

Gene ID: 7056

UniProt: P07204