FcRn antibody (AA 24-297)

Catalog No. ABIN7193244

Product Details anti-FcRn Antibody

Target: FcRn (IgG receptor FcRn (FcRn))

Binding Specificity: AA 24-297

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FcRn antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: FCGRT Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human FCGRT (AA: 24-297) expressed in E. Coli.

Clone: 2B3B11

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for FcRn

Target: FcRn (IgG receptor FcRn (FcRn))

Alternative Name: FCGRT (FcRn Products)

Synonyms: FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody

Background:

Description:

This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.

Aliases: FCRN, alpha-chain

Molecular Weight: 39.7kDa

Gene ID: 2217

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process