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CD53 antibody

CD53 Reactivity: Human FACS, WB, IHC, ELISA Host: Mouse Monoclonal 7A8D3 unconjugated
Catalog No. ABIN7193233
  • Target See all CD53 Antibodies
    CD53
    Reactivity
    • 64
    • 4
    • 3
    Human
    Host
    • 41
    • 23
    Mouse
    Clonality
    • 40
    • 22
    • 2
    Monoclonal
    Conjugate
    • 25
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD53 antibody is un-conjugated
    Application
    • 42
    • 28
    • 25
    • 13
    • 13
    • 12
    • 9
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purpose
    CD53 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD53 (AA: mix) expressed in E. Coli.
    Clone
    7A8D3
    Isotype
    IgG2a
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    CD53
    Alternative Name
    CD53 (CD53 Products)
    Synonyms
    AI323659 antibody, Ox-44 antibody, Tspan25 antibody, MOX44 antibody, TSPAN25 antibody, OX44 antibody, CD53 antigen antibody, CD53 molecule antibody, Cd53 molecule antibody, Cd53 antibody, CD53 antibody
    Background

    Description:

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.

    Aliases: MOX44, TSPAN25

    Molecular Weight
    24.3kDa
    Gene ID
    963
    UniProt
    P19397
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