JAG1 antibody (AA 47-212)

Catalog No. ABIN7193228

Product Details anti-JAG1 Antibody

Target: JAG1 (Jagged 1 (JAG1))

Binding Specificity: AA 47-212

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAG1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD339 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD339 (AA: 47-212) expressed in E. Coli.

Clone: 6A9B2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: CD339 (JAG1 Products)

Synonyms: AGS antibody, AHD antibody, AWS antibody, CD339 antibody, HJ1 antibody, JAGL1 antibody, ABE2 antibody, Gsfabe2 antibody, Htu antibody, Ozz antibody, Ser-1 antibody, JAG1 antibody, jag3 antibody, cb243 antibody, jag1 antibody, sb:cb243 antibody, serrateC antibody, jagged1 antibody, serrate antibody, serrate-1 antibody, x-serrate-1 antibody, jagged 1 antibody, jagged 1b antibody, jagged 1a antibody, jagged 1 L homeolog antibody, JAG1 antibody, Jag1 antibody, jag1 antibody, jag1b antibody, jag1a antibody, jag1.L antibody

Background:

Description:

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Aliases: JAG1, AGS, AHD, AWS, HJ1, AGS1, JAGL1

Molecular Weight: 133.8kDa

Gene ID: 182

UniProt: P78504

Pathways: Notch Signaling, Stem Cell Maintenance