SLAMF6 antibody (AA 22-226)

Catalog No. ABIN7193226

Product Details anti-SLAMF6 Antibody

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Binding Specificity: AA 22-226

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLAMF6 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

Purpose: CD352 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD352 (AA: 22-226) expressed in E. Coli.

Clone: 2F1C9

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SLAMF6

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Alternative Name: CD352 (SLAMF6 Products)

Synonyms: SLAMF6 antibody, CD352 antibody, KALI antibody, KALIb antibody, Ly108 antibody, NTB-A antibody, NTBA antibody, SF2000 antibody, KAL1 antibody, KAL1b antibody, RGD1561848 antibody, SLAM family member 6 antibody, SLAMF6 antibody, Slamf6 antibody

Background:

Description:

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Aliases: SLAMF6, KALI, NTBA, KALIb, Ly108, NTB-A, SF2000

Molecular Weight: 37.4kDa

Gene ID: 114836

UniProt: Q96DU3