PLAUR antibody (AA 23-305)

Catalog No. ABIN7193215

Product Details anti-PLAUR Antibody

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Binding Specificity: AA 23-305

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLAUR antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD87 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD87 (AA: 23-305) expressed in E. Coli.

Clone: 1D1B11

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Alternative Name: CD87 (PLAUR Products)

Synonyms: Cd87 antibody, u-PAR antibody, uPAR antibody, CD87 antibody, U-PAR antibody, UPAR antibody, URKR antibody, Par antibody, Plaur3 antibody, uPAR-2 antibody, uPAR-3 antibody, PLAUR antibody, plasminogen activator, urokinase receptor antibody, Plaur antibody, PLAUR antibody

Background:

Description:

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Aliases: PLAUR, UPAR, URKR, U-PAR

Molecular Weight: 37kDa

Gene ID: 5329

Pathways: Inositol Metabolic Process