Lactoferrin antibody (AA 611-710)

Catalog No. ABIN715091

Product Details anti-Lactoferrin Antibody

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Binding Specificity: AA 611-710

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lactoferrin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Lactoferrin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Lactoferrin antibody (ABIN715091)

Zhao, Ting, Liu, Sun, Kruzel, Roy-OReilly, Aronowski: "Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage." in: Nature communications, Vol. 8, Issue 1, pp. 602, (2018) (PubMed).

Target Details for Lactoferrin

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Alternative Name: Lactoferrin (LTF Products)

Background:

Synonyms: CKRX, GIG12, Growth inhibiting protein 12, HLF2, Homo sapiens chemokine receptor X, Kaliocin 1, Lactoferrin, Lactoferroxin A, Lactoferroxin B, Lactoferroxin C, Lactoferroxin-C, Lactotransferrin, LF, LTF, Neutrophil lactoferrin, Talalactoferrin alfa, Talalactoferrin, TRFL_HUMAN.

Background: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.

Gene ID: 4057

Pathways: Transition Metal Ion Homeostasis