SPAG6 antibody

Catalog No. ABIN7192618

Product Details anti-SPAG6 Antibody

Target: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPAG6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human SPAG6

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SPAG6

Target: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Alternative Name: SPAG6 (SPAG6 Products)

Synonyms: Repro-SA-1 antibody, pf16 antibody, PF16 antibody, RGD1310892 antibody, zgc:91805 antibody, SPAG6 antibody, repro-sa-1 antibody, DKFZp459D035 antibody, sperm associated antigen 6 antibody, sperm associated antigen 6-like antibody, sperm associated antigen 6 L homeolog antibody, SPAG6 antibody, Spag6l antibody, Spag6 antibody, spag6 antibody, spag6.L antibody

Background:

Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm.

Aliases: axoneme central apparatus protein antibody, DKFZp434I153 antibody, MGC26276 antibody, PF16 antibody, PF16 protein homolog antibody, Protein PF16 homolog antibody, Repro SA 1 antibody, Repro-SA-1 antibody, SPAG6 antibody, SPAG6_HUMAN antibody, Sperm associated antigen 6 antibody, Sperm flagellar protein antibody, Sperm-associated antigen 6 antibody

UniProt: O75602