SH2B2 antibody

Catalog No. ABIN7192349

Product Details anti-SH2B2 Antibody

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2B2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human SH2B2

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SH2B2

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Alternative Name: SH2B2 (SH2B2 Products)

Synonyms: APS antibody, Aps antibody, SH2B adaptor protein 2 antibody, SH2B2 antibody, Sh2b2 antibody

Background:

Background: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Aliases: SH2B2 antibody, APS antibody, SH2B adapter protein 2 antibody, Adapter protein with pleckstrin homology and Src homology 2 domains antibody, SH2 and PH domain-containing adapter protein APS antibody

UniProt: O14492

Pathways: Carbohydrate Homeostasis, Brown Fat Cell Differentiation