BIRC3 antibody (AA 511-604) (Biotin)

Catalog No. ABIN714988

Product Details anti-BIRC3 Antibody (Biotin)

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Binding Specificity: AA 511-604

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human cIAP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for BIRC3

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Alternative Name: API2 (BIRC3 Products)

Background:

Synonyms: CIAP 2, CIAP-2, Inhibitor of apoptosis protein 1, AIP 1, AIP1, API 2, API2, Apoptosis inhibitor 2, Baculoviral IAP repeat containing 3, Baculoviral IAP repeat containing protein 3, Baculoviral IAP repeat-containing protein 3, BIRC 3, BIRC3, BIRC3_HUMAN, C IAP2, C-IAP2, CIAP 2, CIAP2, HAIP 1, HAIP1, HIAP 1, HIAP-1, HIAP1, IAP homolog C, IAP-1, Inhibitor of apoptosis protein 1, MALT 2, MALT2, Mammalian IAP homolog C, MIHC, RING finger protein 49, RNF49, TNFR2 TRAF signaling complex protein 1, TNFR2 TRAF signalling complex protein, TNFR2-TRAF-signaling complex protein 1.

Background: Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).

Gene ID: 330

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades