IGLV1-51 antibody

Catalog No. ABIN7191260

Product Details anti-IGLV1-51 Antibody

Target: IGLV1-51 (Immunoglobulin lambda Variable 1-51 (IGLV1-51))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGLV1-51 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human Lambda Light chain

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IGLV1-51

Target: IGLV1-51 (Immunoglobulin lambda Variable 1-51 (IGLV1-51))

Alternative Name: IGLV1-51 (IGLV1-51 Products)

Synonyms: IGLV151 antibody, V1-19 antibody, immunoglobulin lambda variable 1-51 antibody, IGLV1-51 antibody

Background:

Background: Antibody producing cells of the immune system require multiple rearrangements of immunoglobulin (antibody, Ig) genes. Immunoglobulins are four-chain, Y-shaped, monomeric structures of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. Immunoglobulins in vertebrates help to remove non-self molecules or cells (antigens) by recognizing and binding to the antigen and carrying out effector functions that activate the immune system. Variable genetic combinations of the five heavy chain classes (M, D, G, E and A) and the two light chain isotypes, Kappa and Lambda, confer the role of an antibody. The variable region genes encoding immunoglobulin Kappa and Lambda chains are assembled from three DNA segments, the V, C and J genes. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin.

Aliases: IGLV1-51Immunoglobulin lambda variable 1-51 antibody, Ig lambda chain V-I region BL2 antibody, Ig lambda chain V-I region EPS antibody, Ig lambda chain V-I region NEW antibody, Ig lambda chain V-I region NIG-64 antibody

UniProt: P01701