HIST1H2AB antibody

Catalog No. ABIN7190953

Product Details anti-HIST1H2AB Antibody

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2AB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human HIST1H2AB

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HIST1H2AB

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Alternative Name: HIST1H2AB (HIST1H2AB Products)

Synonyms: H2A/m antibody, H2AFM antibody, H2A.1 antibody, H2a-53 antibody, histone cluster 1 H2A family member b antibody, histone cluster 1, H2ab antibody, HIST1H2AB antibody, Hist1h2ab antibody

Background:

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Aliases: H2a 615 antibody, H2A antibody, H2A GL101 antibody, H2A histone family member A antibody, H2A.1 antibody, H2A.2 antibody, H2A/a antibody, H2A/m antibody, H2A/O antibody, H2A/q antibody, H2A1B_HUMAN antibody, H2AFA antibody, H2AFE antibody, H2AFL antibody, H2AFM antibody, H2AFO antibody, H2AFQ antibody, HIST1H2AE antibody, HIST1H2AJ antibody, HIST2H2AA antibody, HIST2H2AA3 antibody, HIST2H2AB antibody, HIST2H2AC antibody, Histone 1 H2ae antibody, Histone 2 H2aa3 antibody, Histone 2 H2ab antibody, Histone 2 H2ac antibody, Histone H2A type 1 B antibody, Histone H2A type 1 C antibody, Histone H2A type 1 E antibody, Histone H2A type 1 J antibody, Histone H2A type 1-B/E antibody, Histone H2A.2 antibody, Histone H2A/a antibody, Histone H2A/m antibody, MGC74460 antibody

UniProt: P04908

Pathways: Telomere Maintenance