FAT4 antibody
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- Target See all FAT4 Antibodies
- FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FAT4 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human FAT4
- Isotype
- IgG
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- Application Notes
- ELISA:1:2000-1:5000, IHC:1:25-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
- Alternative Name
- FAT4 (FAT4 Products)
- Synonyms
- CDHF14 antibody, CDHR11 antibody, FAT-J antibody, FATJ antibody, NBLA00548 antibody, 6030410K14Rik antibody, 9430004M15 antibody, FAT atypical cadherin 4 antibody, FAT4 antibody, Fat4 antibody
- Background
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Background: FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by γ secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.
Aliases: Cadherin family member 14 antibody, Cadherin related family member 11 antibody, CDHF14 antibody, CDHR11 antibody, FAT atypical cadherin 4 antibody, FAT J antibody, FAT tumor suppressor homolog 4 antibody, Fat-like cadherin protein FAT-J antibody, FAT4 antibody, FAT4_HUMAN antibody, FATJ antibody, hFat4 antibody, HKLLS2 antibody, Nbla00548 antibody, Protocadherin Fat 4 antibody, Putative protein product of Nbla00548 antibody, VMLDS2 antibody
- UniProt
- Q6V0I7
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