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EID3 antibody

EID3 Reactivity: Human ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7190538
  • Target See all EID3 Antibodies
    EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))
    Reactivity
    • 10
    • 8
    Human
    Host
    • 9
    • 1
    Rabbit
    Clonality
    • 9
    • 1
    Polyclonal
    Conjugate
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EID3 antibody is un-conjugated
    Application
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of Human EID3
    Isotype
    IgG
  • Application Notes
    ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))
    Alternative Name
    EID3 (EID3 Products)
    Synonyms
    NS4EB antibody, NSE4B antibody, NSMCE4B antibody, 1700027M21Rik antibody, EP300 interacting inhibitor of differentiation 3 antibody, EID3 antibody, Eid3 antibody
    Background

    Background: EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.

    Aliases: E1A-like inhibitor of differentiation 3 antibody, EID 3 antibody, EID-1-like inhibitor of differentiation 3 antibody, EID-3 antibody, EID3 antibody, EID3_HUMAN antibody, EP300 interacting inhibitor of differentiation 3 antibody, EP300-interacting inhibitor of differentiation 3 antibody, FLJ25832 antibody, Non-SMC element 4, S. cerevisiae, homolog of, B antibody, Non-structural maintenance of chromosomes element 4 homolog B antibody, NSE4B antibody, NSMCE4B antibody

    UniProt
    Q8N140
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