EID3 antibody
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- Target See all EID3 Antibodies
- EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EID3 antibody is un-conjugated
- Application
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human EID3
- Isotype
- IgG
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- Application Notes
- ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))
- Alternative Name
- EID3 (EID3 Products)
- Synonyms
- NS4EB antibody, NSE4B antibody, NSMCE4B antibody, 1700027M21Rik antibody, EP300 interacting inhibitor of differentiation 3 antibody, EID3 antibody, Eid3 antibody
- Background
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Background: EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.
Aliases: E1A-like inhibitor of differentiation 3 antibody, EID 3 antibody, EID-1-like inhibitor of differentiation 3 antibody, EID-3 antibody, EID3 antibody, EID3_HUMAN antibody, EP300 interacting inhibitor of differentiation 3 antibody, EP300-interacting inhibitor of differentiation 3 antibody, FLJ25832 antibody, Non-SMC element 4, S. cerevisiae, homolog of, B antibody, Non-structural maintenance of chromosomes element 4 homolog B antibody, NSE4B antibody, NSMCE4B antibody
- UniProt
- Q8N140
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