Claudin 19 antibody

Catalog No. ABIN7190275

Product Details anti-Claudin 19 Antibody

Target: Claudin 19 (CLDN19)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 19 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human CLDN19

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Claudin 19

Target: Claudin 19 (CLDN19)

Alternative Name: CLDN19 (CLDN19 Products)

Synonyms: HOMG5 antibody, claudin-19 antibody, zgc:112141 antibody, claudin 19 antibody, claudin 19 S homeolog antibody, CLDN19 antibody, Cldn19 antibody, cldn19.S antibody, cldn19 antibody

Background:

Background: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Aliases: CLDN19Claudin-19 antibody

UniProt: Q8N6F1

Pathways: Cell-Cell Junction Organization, Hepatitis C