FLASH antibody

Catalog No. ABIN7190062

Product Details anti-FLASH Antibody

Target: FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLASH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human CASP8AP2

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FLASH

Target: FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

Alternative Name: CASP8AP2 (CASP8AP2 Products)

Synonyms: CASP8AP2 antibody, FLASH antibody, fc74h10 antibody, wu:fc74h10 antibody, zgc:113449 antibody, CED-4 antibody, RIP25 antibody, AA387232 antibody, D4Ertd659e antibody, mKIAA1315 antibody, caspase 8 associated protein 2 antibody, CASP8AP2 antibody, casp8ap2 antibody, Casp8ap2 antibody

Background:

Background: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Aliases: AA387232 antibody, C8AP2_HUMAN antibody, CASP 8 associated protein 2 antibody, CASP8 associated protein 2 antibody, CASP8-associated protein 2 antibody, CASP8AP2 antibody, Caspase 8 associated protein 2 antibody, CED 4 antibody, CED4 antibody, D4Ertd659e antibody, FLASH homolog antibody, FLASH homolog RIP 25 antibody, FLASH homolog RIP25 antibody, FLICE associated huge antibody, FLICE associated huge protein antibody, FLICE-associated huge protein antibody, FLJ11208 antibody, KIAA1315 antibody, mKIAA1315 antibody, OTTMUSP00000005125 antibody, RIP 25 antibody, RIP25 antibody, RP23-69G24.1 antibody

UniProt: Q9UKL3

Pathways: Chromatin Binding, Positive Regulation of Endopeptidase Activity