ANKRD28 antibody

Catalog No. ABIN7189809

Product Details anti-ANKRD28 Antibody

Target: ANKRD28 (Ankyrin Repeat Domain 28 (ANKRD28))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD28 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human ANKRD28

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ANKRD28

Target: ANKRD28 (Ankyrin Repeat Domain 28 (ANKRD28))

Alternative Name: ANKRD28 (ANKRD28 Products)

Synonyms: PITK antibody, PPP1R65 antibody, AI465466 antibody, AI604979 antibody, E430019N21Rik antibody, mKIAA0379 antibody, RGD1559931 antibody, ANKRD28 antibody, ankyrin repeat domain 28 antibody, ankyrin repeat domain 28b antibody, ANKRD28 antibody, Ankrd28 antibody, ankrd28b antibody, ankrd28 antibody

Background:

Background: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.

Aliases: ANKRD28 antibody, KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody, PP6-ARS-A antibody, Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody, Ankyrin repeat domain-containing protein 28 antibody, Phosphatase interactor targeting protein hnRNP K antibody, PITK antibody

UniProt: O15084