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ARHGAP24 antibody (AA 501-600)

ARHGAP24 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN714716
  • Target See all ARHGAP24 Antibodies
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Binding Specificity
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    AA 501-600
    Reactivity
    • 27
    • 10
    • 10
    • 1
    • 1
    Human
    Host
    • 25
    • 2
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGAP24 antibody is un-conjugated
    Application
    • 20
    • 16
    • 3
    Western Blotting (WB), ELISA
    Predicted Reactivity
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ARHGAP24
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Alternative Name
    ARHGAP24 (ARHGAP24 Products)
    Synonyms
    FILGAP antibody, RC-GAP72 antibody, RCGAP72 antibody, p73 antibody, p73RhoGAP antibody, 0610025G21Rik antibody, si:ch211-65i12.2 antibody, Rho GTPase activating protein 24 antibody, ARHGAP24 antibody, Arhgap24 antibody, arhgap24 antibody
    Background

    Synonyms: Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, ARHGAP24, FILGAP

    Background: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

    Gene ID
    83478
    UniProt
    Q8N264
    Pathways
    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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