PDGFD antibody (AA 271-370)

Catalog No. ABIN714581

Product Details anti-PDGFD Antibody

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Binding Specificity: AA 271-370

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDGF-D

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PDGFD antibody (ABIN714581)

Hurley, Adams, Wang, Jiang, Meo Burt, Du, Xiao: "Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2." in: Journal of cellular biochemistry, (2015) (PubMed).

Target Details for PDGFD

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Alternative Name: PDGF D (PDGFD Products)

Synonyms: IEGF antibody, SCDGF-B antibody, SCDGFB antibody, Scdgfb antibody, rSCDGF-B antibody, PDGFD antibody, 1110003I09Rik antibody, platelet derived growth factor D antibody, platelet-derived growth factor, D polypeptide antibody, PDGFD antibody, Pdgfd antibody

Background:

Synonyms: IEGF, SCDGFB, MSTP036, SCDGF-B, Platelet-derived growth factor D, PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, PDGFD, UNQ1899/PRO4345

Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).

Gene ID: 80310

UniProt: Q9GZP0

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling