PDGFC antibody (AA 201-300) (Biotin)

Catalog No. ABIN714568

Product Details anti-PDGFC Antibody (Biotin)

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Binding Specificity: AA 201-300

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFC antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDGFC/VEGF E

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PDGFC

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Alternative Name: PDGF C (PDGFC Products)

Synonyms: SCDGF antibody, FALLOTEIN antibody, 1110064L01Rik antibody, AI647969 antibody, PDGF-C antibody, platelet derived growth factor C antibody, platelet-derived growth factor, C polypeptide antibody, PDGFC antibody, Pdgfc antibody

Target Type: Viral Protein

Background:

Synonyms: SCDGF, FALLOTEIN, Platelet-derived growth factor C, PDGF-C, Spinal cord-derived growth factor, VEGF-E, PDGFC, UNQ174/PRO2

Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.

Gene ID: 56034

UniProt: Q9NRA1

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling