FGF23 antibody (AA 21-120)
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- Target See all FGF23 Antibodies
- FGF23 (Fibroblast Growth Factor 23 (FGF23))
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Binding Specificity
- AA 21-120
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FGF23 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FGF23
- Isotype
- IgG
- Top Product
- Discover our top product FGF23 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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Cardiac FGF23: new insights into the role and function of FGF23 after acute myocardial infarction." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 40, pp. 47-54, (2019) (PubMed).
: "Elevation of circulating but not myocardial FGF23 in human acute decompensated heart failure." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 31, Issue 5, pp. 767-72, (2016) (PubMed).
: "
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Cardiac FGF23: new insights into the role and function of FGF23 after acute myocardial infarction." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 40, pp. 47-54, (2019) (PubMed).
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- Target
- FGF23 (Fibroblast Growth Factor 23 (FGF23))
- Alternative Name
- FGF23 (FGF23 Products)
- Synonyms
- FGF23 antibody, ADHR antibody, FGFN antibody, HPDR2 antibody, HYPF antibody, PHPTC antibody, fibroblast growth factor 23 antibody, fgf23 antibody, FGF23 antibody, Fgf23 antibody
- Background
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Synonyms: ADHR, FGFN, HYPF, HPDR2, PHPTC, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor, FGF23, UNQ327/PRO9828
Background: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
- Gene ID
- 8074
- UniProt
- Q9GZV9
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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