Epigen antibody (AA 51-130)

Catalog No. ABIN714446

Product Details anti-Epigen Antibody

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Binding Specificity: AA 51-130

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epigen antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Epigen

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Epigen

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Alternative Name: Epigen (EPGN Products)

Synonyms: ALGV3072 antibody, EPG antibody, PRO9904 antibody, 2310069M11Rik antibody, epigen antibody, RGD1560084 antibody, epithelial mitogen antibody, EPGN antibody, Epgn antibody

Background:

Synonyms: EPG, Epigen precursor, Epithelial mitogen, EPGN_HUMAN.

Background: Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.

Gene ID: 255324

Pathways: RTK Signaling, EGFR Signaling Pathway