SPA17 antibody (AA 21-120) (Biotin)

Catalog No. ABIN714253

Product Details anti-SPA17 Antibody (Biotin)

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPA17 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SP17/CT22

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SPA17

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Alternative Name: SP17 (SPA17 Products)

Synonyms: spa17 antibody, MGC89454 antibody, SPA17 antibody, CT22 antibody, SP17 antibody, SP17-1 antibody, Sp17 antibody, sperm autoantigenic protein 17 antibody, sperm autoantigenic protein 17 L homeolog antibody, spa17 antibody, SPA17 antibody, spa17.L antibody, Spa17 antibody

Background:

Synonyms: Band 34, Cancer/testis antigen 22, CT22, SP17 1, Sp17-1, SP17_HUMAN, SPA17, Sperm autoantigenic protein 17, Sperm protein 17, Sperm surface protein Sp17.

Background: SP17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009].

Gene ID: 53340