NKX3-1 antibody (N-Term)

Catalog No. ABIN7184486

Product Details anti-NKX3-1 Antibody

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX3-1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human NKX3.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Alternative Name: NKX3-1 (NKX3-1 Products)

Synonyms: Xbagpipe antibody, Xbap antibody, bagpipe antibody, koza antibody, nkx3-1 antibody, nkx3.1 antibody, si:ch211-67o1.2 antibody, nkx3a antibody, MGC53041 antibody, MGC97890 antibody, Bax antibody, NKX3.1 antibody, NKX3A antibody, Nkx-3.1 antibody, BAPX2 antibody, NKX3 antibody, NK3 homeobox 1 L homeolog antibody, NK3 homeobox 1 antibody, NK-3 transcription factor, locus 1 (Drosophila) antibody, nkx3-1.L antibody, NKX3-1 antibody, nkx3-1 antibody, Nkx3-1 antibody

Background:

Background: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Cai Bowen, Cancer Res., Jan 2007, 67: 455 - 464.
Xiang Li, Mol. Cell. Biol., Apr 2006, 26: 3008 - 3017.
Ekatherine Asatiani, Cancer Res., Feb 2005, 65: 1164 - 1173.
Carlise R. Bethel, Cancer Res., Nov 2006, 66: 10683 - 10690.

Aliases: BAPX 2 antibody, BAPX2 antibody, Homeobox protein NK-3 homolog A antibody, Homeobox protein Nkx 3.1 antibody, Homeobox protein Nkx-3.1 antibody, Homeobox protein Nkx3.1 antibody, NK homeobox (Drosophila) family 3 A antibody, NK homeobox family 3 A antibody, NK homeobox, family 3, member A antibody, NK3 homeobox 1 antibody, NK3 transcription factor homolog A antibody, NK3 transcription factor related locus 1 antibody, NKX 3 antibody, Nkx 3.1 antibody, NKX 3A antibody, NKX3 1 antibody, NKX3 antibody, Nkx3-1 antibody, NKX3.1 antibody, Nkx3.1, mouse, homolog of antibody, NKX31_HUMAN antibody, NKX3A antibody

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus