HES6 antibody (N-Term)

Catalog No. ABIN7184460

Product Details anti-HES6 Antibody

Target: HES6 (Hairy and Enhancer of Split 6 (HES6))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HES6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human HES6.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HES6

Target: HES6 (Hairy and Enhancer of Split 6 (HES6))

Alternative Name: HES6 (HES6 Products)

Synonyms: YF-30 antibody, her13.2 antibody, AI326893 antibody, bHLHb41 antibody, HES-6 antibody, bHLHc23 antibody, hes family bHLH transcription factor 6 antibody, hairy and enhancer of split 6 antibody, hes6 antibody, Hes6 antibody, HES6 antibody

Background:

Background: Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation By similarity. UniProtKB Q9JHE6

Bae S.-K., Development 127:2933-2943(2000).
Vasiliauskas D., Mech. Dev. 98:133-137(2000).
Ota T., Nat. Genet. 36:40-45(2004).

Aliases: HES6 antibody, BHLHB41 antibody, Transcription cofactor HES-6 antibody, C-HAIRY1 antibody, Class B basic helix-loop-helix protein 41 antibody, bHLHb41 antibody, Hairy and enhancer of split 6 antibody

UniProt: Q96HZ4