DOK7 antibody (N-Term)

Catalog No. ABIN7184448

Product Details anti-DOK7 Antibody

Target: DOK7 (Docking Protein 7 (DOK7))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human DOK7.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DOK7

Target: DOK7 (Docking Protein 7 (DOK7))

Alternative Name: DOK7 (DOK7 Products)

Synonyms: si:dkey-180b4.3 antibody, si:ch211-164d19.2 antibody, C4orf25 antibody, CMS1B antibody, A930013K19Rik antibody, AW049091 antibody, Dok-7 antibody, EF-12 antibody, Oit5 antibody, RGD1566416 antibody, dok-7 antibody, docking protein 7 antibody, DOK7 antibody, dok7 antibody, Dok7 antibody

Background:

Background: Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.

Okada K., Science 312:1802-1805(2006).
Ota T., Nat. Genet. 36:40-45(2004).
Beeson D., Science 313:1975-1978(2006).

Aliases: Docking protein 7 antibody, DOK 7 antibody, DOK7 antibody, DOK7_HUMAN antibody, Downstream of tyrosine kinase 7 antibody, Protein Dok-7 antibody

UniProt: Q18PE1

Pathways: Skeletal Muscle Fiber Development