AF4 antibody (N-Term)

Catalog No. ABIN7184411

Product Details anti-AF4 Antibody

Target: AF4 (AFF1) (AF4/FMR2 Family, Member 1 (AFF1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AF4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human AF4.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AF4

Target: AF4 (AFF1) (AF4/FMR2 Family, Member 1 (AFF1))

Alternative Name: AFF1 (AFF1 Products)

Synonyms: AF4 antibody, MLLT2 antibody, PBM1 antibody, 9630032B01Rik antibody, AW319193 antibody, Af4 antibody, Mllt2h antibody, Rob antibody, Mllt2 antibody, AF4/FMR2 family member 1 antibody, AF4/FMR2 family, member 1 antibody, AFF1 antibody, Aff1 antibody

Background:

Background: A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4,11)(q21,q23) with MLL/HRX. The result is a rogue activator protein. Belongs to the AF4 family.?Nakamura T., Proc. Natl. Acad. Sci. U.S.A. 90:4631-4635(1993).Morrissey J., Blood 81:1124-1131(1993).Gu Y., Cell 71:701-708(1992).

Aliases: AF 4 antibody, AF 4 protein antibody, AF4 antibody, AF4-MLL antibody, AF4/FMR2 family member 1 antibody, AFF 1 antibody, AFF1 antibody, AFF1_HUMAN antibody, ALL1 fused gene from chromosome 4 antibody, ALL1-fused gene from chromosome 4 protein antibody, FEL antibody, MGC134969 antibody, MLL/AF4 antibody, MLLT2 antibody, myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila), translocated to, 2 antibody, MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA TRANSLOCATED TO 2, MLLT2 antibody, PBM1 antibody, Pre B cell monocytic leukemia partner 1 antibody, Protein AF-4 antibody, Protein FEL antibody, Proto-oncogene AF4 antibody

UniProt: P51825