Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

TSEN54 antibody

TSEN54 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7184298
  • Target See all TSEN54 Antibodies
    TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))
    Reactivity
    • 13
    • 9
    • 1
    Human
    Host
    • 12
    • 1
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSEN54 antibody is un-conjugated
    Application
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from internal of Human TSEN54.
    Isotype
    IgG
    Top Product
    Discover our top product TSEN54 Primary Antibody
  • Application Notes
    WB:1:500-1:3000, IHC:1:50-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))
    Alternative Name
    TSEN54 (TSEN54 Products)
    Synonyms
    zgc:109927 antibody, 0610034P02Rik antibody, PCH2A antibody, PCH4 antibody, SEN54L antibody, sen54 antibody, tRNA splicing endonuclease subunit 54 antibody, TSEN54 tRNA splicing endonuclease subunit antibody, tRNA splicing endonuclease 54 homolog (S. cerevisiae) antibody, TSEN54 antibody, tsen54 antibody, Tsen54 antibody
    Background

    Background: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.

    Zody M.C., Nature 440:1045-1049(2006).
    Paushkin S.V., Cell 117:311-321(2004).
    Ota T., Nat. Genet. 36:40-45(2004).

    Aliases: HsSen54 antibody, PCH2A antibody, PCH4 antibody, sen54 antibody, SEN54 homolog antibody, SEN54_HUMAN antibody, SEN54L antibody, tRNA-intron endonuclease SEN54 antibody, tRNA-splicing endonuclease subunit SEN54 antibody, Tsen54 antibody, TSEN54 tRNA splicing endonuclease subunit antibody

    UniProt
    Q7Z6J9
    Pathways
    Synaptic Membrane
You are here:
Support