MATK antibody (AA 411-507)

Catalog No. ABIN714206

Product Details anti-MATK Antibody

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Binding Specificity: AA 411-507

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MATK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MATK

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MATK

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Alternative Name: MATK (MATK Products)

Synonyms: si:ch211-63j24.2 antibody, CHK antibody, CTK antibody, HHYLTK antibody, HYL antibody, HYLTK antibody, Lsk antibody, Ntk antibody, Batk antibody, megakaryocyte-associated tyrosine kinase antibody, zinc finger RNA binding protein 2 antibody, matk antibody, MATK antibody, Matk antibody, ZFR2 antibody

Background:

Synonyms: CHK, Csk homologous kinase, Csk type protein tyrosine kinase, CTK, Hematopoietic consensus tyrosine lacking kinase, HHYLTK, Hydroxyaryl protein kinase, HYL, HYL tyrosine kinase, HYLTK, Leukocyte carboxyl terminal src kinase related, Lsk, Megakaryocyte associated tyrosine kinase, Megakaryocyte associated tyrosine protein kinase, Protein kinase HYL, Tyrosine kinase MATK, Tyrosine protein kinase CTK, Tyrosylprotein kinase, MATK_HUMAN.

Background: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Gene ID: 4145