KSR2 antibody
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- Target See all KSR2 Antibodies
- KSR2 (Kinase Suppressor of Ras 2 (KSR2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KSR2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from internal of Human KSR2.
- Isotype
- IgG
- Top Product
- Discover our top product KSR2 Primary Antibody
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anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibody
KSR2 Reactivity: Human ELISA, WB, RNAi Host: Mouse Monoclonal 1G4 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 Reactivity: Human ELISA, WB, IF Host: Mouse Monoclonal 6C9 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 603-638), (C-Term) antibodyKSR2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB09886 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 159-296) antibodyKSR2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (Internal Region) antibodyKSR2 Reactivity: Human, Mouse ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (C-Term) antibodyKSR2 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 1-829) antibodyKSR2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 Reactivity: Human ELISA, WB Host: Mouse Monoclonal 6F12 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (Ile694) antibodyKSR2 Reactivity: Human, Mouse WB, IHC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB:1:500-1:3000, IF:1:100-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- KSR2 (Kinase Suppressor of Ras 2 (KSR2))
- Alternative Name
- KSR2 (KSR2 Products)
- Synonyms
- kinase suppressor of ras 2 antibody, KSR2 antibody, Ksr2 antibody
- Background
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Background:
Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Ota T., Nat. Genet. 36:40-45(2004).
Scherer S.E., Nature 440:346-351(2006).
Channavajhala P.L., J. Biol. Chem. 278:47089-47097(2003).Aliases: FLJ25965 antibody, hKSR 2 antibody, hKSR2 antibody, Kinase suppressor of Ras 2 antibody, KSR 2 antibody, Ksr2 antibody, KSR2_HUMAN antibody
- UniProt
- Q6VAB6
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