CK1 epsilon antibody

Catalog No. ABIN7183325

Product Details anti-CK1 epsilon Antibody

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CK1 epsilon antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human CKI-ε,.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CK1 epsilon

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Alternative Name: CSNK1E (CSNK1E Products)

Background:

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.

Fish K.J., J. Biol. Chem. 270:14875-14883(1995).
Okamura A., Blood 103:2997-3004(2004).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Aliases: Casein kinase 1 epsilon antibody, Casein kinase I antibody, Casein kinase I epsilon antibody, Casein kinase I isoform epsilon antibody, CKI epsilon antibody, CKI-epsilon antibody, CKIe antibody, CKIepsilon antibody, CSNK 1E antibody, CSNK1E antibody, DBT antibody, Doubletime, Drosophila, homolog of antibody, EC 2.7.11.1 antibody, epsilon isoform antibody, HCK IE antibody, KC1E antibody, KC1E_HUMAN antibody, kinase CK1 epsilon antibody, MGC 10398 antibody

UniProt: P49674

Pathways: Hedgehog Signaling, M Phase