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GRM8 antibody

GRM8 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7181343
  • Target See all GRM8 Antibodies
    GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
    Reactivity
    • 30
    • 23
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    • 3
    Rabbit
    Clonality
    • 28
    • 2
    Polyclonal
    Conjugate
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRM8 antibody is un-conjugated
    Application
    • 18
    • 12
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from Human GluR8.
    Isotype
    IgG
    Top Product
    Discover our top product GRM8 Primary Antibody
  • Application Notes
    WB:1:500-1:3000, IHC:1:50-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
    Alternative Name
    GRM8 (GRM8 Products)
    Background

    Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

    Patrick. M. Downey, J Biomol Screen, Dec 2005, 10: 841 - 848.
    RJ Wenthold, J. Biol. Chem., Jan 1994, 269: 1332 - 1339.
    Toshiaki Watanabe, Cancer Res., Oct 2006, 66: 9804 - 9808.
    V. Bruno, J. Neurosci., Sep 2000, 20: 6413.

    Aliases: FLJ41058 antibody, GLUR8 antibody, Glutamate receptor metabotropic 8 antibody, GPRC1H antibody, GRM8 antibody, GRM8_HUMAN antibody, Metabotropic glutamate receptor 8 antibody, MGC126724 antibody, mGlu8 antibody, mGluR8 antibody

    UniProt
    O00222
    Pathways
    cAMP Metabolic Process, Synaptic Membrane
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