ARC antibody

Catalog No. ABIN7180447

Product Details

Target: ARC

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Human ARC.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: ARC

Synonyms: activity regulated cytoskeleton associated protein antibody, Arc antibody

Background:

Background: This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene.

Victor Ram?z-Amaya, J. Neurosci., Feb 2005, 25: 1761 - 1768.
Young-Jae Nam, J. Biol. Chem., Feb 2007, 282: 5522 - 5528.
Daryoush Ekhterae, Circ. Res., Dec 1999, 85: 70.
Tsai-Kun Li, Cancer Res., Dec 2003, 63: 8400 - 8407

Aliases: Myp, NOL3, Nop30, Nucleolar protein 3, apoptosis repressor ARC

UniProt: Q5TZN6