SHB antibody (C-Term)

Catalog No. ABIN7180246

Product Details anti-SHB Antibody

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human SHB.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SHB

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Alternative Name: SHB (SHB Products)

Synonyms: SHB antibody, RP11-3J10.8 antibody, bA3J10.2 antibody, RGD1565350 antibody, BC028832 antibody, SH2 domain containing adaptor protein B antibody, src homology 2 domain-containing transforming protein B antibody, SHB antibody, Shb antibody

Background:

Background: Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Welsh M., Oncogene 9:19-27(1994).
Humphray S.J., Nature 429:369-374(2004).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

Aliases: bA3J10.2 antibody, OTTHUMP00000021397 antibody, RP11 3J10.8 antibody, RP113J10.8 antibody, SH2 domain containing adapter protein B antibody, SH2 domain-containing adapter protein B antibody, SHB (Src homology 2 domain containing) adaptor protein B antibody, SHB adaptor protein (a Src homology 2 protein) antibody, SHB adaptor protein antibody, Shb antibody, SHB_HUMAN antibody, Src homology 2 domain containing adaptor protein B antibody, Src homology 2 protein antibody

UniProt: Q15464