POLR1B antibody (C-Term)

Catalog No. ABIN7180222

Product Details anti-POLR1B Antibody

Target: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human POLR1B.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for POLR1B

Target: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Alternative Name: POLR1B (POLR1B Products)

Synonyms: RPOL-1l antibody, MGC68946 antibody, 128kDa antibody, D630020H17Rik antibody, RPA116 antibody, RPA135 antibody, RPA2 antibody, Rpo1-2 antibody, RNA polymerase I subunit B antibody, polymerase (RNA) I polypeptide B L homeolog antibody, polymerase (RNA) I polypeptide B, 128kDa antibody, polymerase (RNA) I polypeptide B antibody, DNA-directed RNA polymerase I subunit RPA2 antibody, POLR1B antibody, polr1b.L antibody, polr1b antibody, LOC100563266 antibody, LOC100634236 antibody, Polr1b antibody

Background:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft By similarity.

Ota T., Nat. Genet. 36:40-45(2004).
Hillier L.W., Nature 434:724-731(2005).
Miller G., EMBO J. 20:1373-1382(2001).

Aliases: A127 antibody, DNA directed RNA polymerase I 135 kDa polypeptide antibody, DNA directed RNA polymerase I antibody, DNA directed RNA polymerase I subunit RPA2 antibody, DNA-directed RNA polymerase I 135 kDa polypeptide antibody, DNA-directed RNA polymerase I subunit rpa2 antibody, FLJ10816 antibody, FLJ21921 antibody, MGC131780 antibody, OTTHUMP00000161989 antibody, OTTHUMP00000203643 antibody, OTTHUMP00000203645 antibody, POLR 1B antibody, polr1b antibody, Polymerase (RNA) I polypeptide B 128 kDa antibody, Polymerase (RNA) I polypeptide B antibody, RNA polymerase I polypeptide B antibody, RNA polymerase I subunit 2 antibody, RPA 135 antibody, RPA116 antibody, RPA135 antibody, RPA2 antibody, RPA2_HUMAN antibody, Rpo1 2 antibody

UniProt: Q9H9Y6