NUB1 antibody (C-Term)
-
- Target See all NUB1 Antibodies
- NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
-
Binding Specificity
- C-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This NUB1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human, Mouse
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from C-terminal of Human NYREN18.
- Isotype
- IgG
- Top Product
- Discover our top product NUB1 Primary Antibody
-
-
- Application Notes
- WB:1:500-1:3000, IHC:1:50-1:100,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
- Alternative Name
- NUB1 (NUB1 Products)
- Synonyms
- BS4 antibody, NYREN18 antibody, NUB1L antibody, 4931404D21Rik antibody, 6330412F12Rik antibody, NY-REN-18 antibody, negative regulator of ubiquitin-like proteins 1 antibody, negative regulator of ubiquitin like proteins 1 antibody, Nub1 antibody, NUB1 antibody
- Background
-
Background: Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
Sarah M. Mense, Toxicol. Sci., Sep 2006, 93: 125 - 135.
Gunter Schmidtke, J. Biol. Chem., Jul 2006, 281: 20045 - 20054.s
Kunikazu Tanji, Am. J. Pathol., Aug 2006, 169: 553 - 565.
Miguel Ramalho-Santos, Science, Oct 2002, 298: 597.Aliases: BS4 antibody, NEDD8 µLtimate buster 1 antibody, Negative regulator of ubiquitin like proteins 1 antibody, Negative regulator of ubiquitin-like proteins 1 antibody, NUB1 antibody, NUB1_HUMAN antibody, NUB1L antibody, NY REN 18 antibody, NYREN18 antibody, Renal carcinoma antigen NY-REN-18 antibody
- UniProt
- Q9Y5A7
-