MRPL2 antibody (C-Term)

Catalog No. ABIN7180206

Product Details anti-MRPL2 Antibody

Target: MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human MRPL20.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MRPL2

Target: MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))

Alternative Name: MRPL2 (MRPL2 Products)

Synonyms: MRP-L14 antibody, RPML14 antibody, CGI-22 antibody, Rpml14 antibody, mitochondrial ribosomal protein L2 antibody, MRPL2 antibody, Mrpl2 antibody

Background:

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q.

Suzuki T., J. Biol. Chem. 276:21724-21736(2001).
Gregory S.G., Nature 441:315-321(2006).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: MRPL20 antibody, 39S ribosomal protein L20 antibody, mitochondrial antibody, L20mt antibody, MRP-L20 antibody, Mitochondrial large ribosomal subunit protein bL20m antibody

UniProt: Q9BYC9