MNDA antibody (C-Term)

Catalog No. ABIN7180203

Product Details anti-MNDA Antibody

Target: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MNDA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human MNDA.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MNDA

Target: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Alternative Name: MNDA (MNDA Products)

Synonyms: PYHIN3 antibody, A730048F03 antibody, Ifi205b antibody, myeloid cell nuclear differentiation antigen antibody, interferon activated gene 211 antibody, MNDA antibody, Ifi211 antibody

Background:

Background: The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.

Briggs J.A., J. Cell. Biochem. 49:82-92(1992).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Burrus G.R., J. Cell. Biochem. 48:190-202(1992).

Aliases: MNDA antibody, MNDA_HUMAN antibody, Myeloid cell nuclear differentiation antigen antibody, OTTHUMP00000024384 antibody, PYHIN3 antibody

UniProt: P41218