Ephrin A3 antibody (C-Term)

Catalog No. ABIN7180164

Product Details anti-Ephrin A3 Antibody

Target: Ephrin A3 (EFNA3)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human EFNA3.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ephrin A3

Target: Ephrin A3 (EFNA3)

Alternative Name: EFNA3 (EFNA3 Products)

Synonyms: efna3 antibody, D160 antibody, ephrin-A3 antibody, zgc:100772 antibody, AW494418 antibody, EFL-2 antibody, Ehk1-L antibody, Epl3 antibody, LERK-3 antibody, MGC64593 antibody, EFL2 antibody, EPLG3 antibody, LERK3 antibody, ephrin A3 antibody, ephrin-A3b antibody, ephrin A3 L homeolog antibody, efna3 antibody, EFNA3 antibody, efna3b antibody, Efna3 antibody, efna3.L antibody

Background:

Background: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling By similarity.

Kozlosky C.J., Oncogene 10:299-306(1995).
Davis S., Science 266:816-819(1994).
Gregory S.G., Nature 441:315-321(2006).

Aliases: EFL 2 antibody, EFL-2 antibody, EFL2 antibody, EFN A3 antibody, EFNA 3 antibody, Efna3 antibody, EFNA3_HUMAN antibody, EHK1 L antibody, EHK1 ligand antibody, EHK1-L antibody, EHK1L antibody, EPH related receptor tyrosine kinase ligand 3 antibody, EPH-related receptor tyrosine kinase ligand 3 antibody, Ephrin-A3 antibody, EphrinA3 antibody, EPLG 3 antibody, EPLG3 antibody, LERK 3 antibody, LERK-3 antibody, LERK3 antibody, Ligand of eph related kinase 3 antibody

UniProt: P52797

Pathways: RTK Signaling