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DMGDH antibody (C-Term)

DMGDH Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7180160
  • Target See all DMGDH Antibodies
    DMGDH (Dimethylglycine Dehydrogenase (DMGDH))
    Binding Specificity
    • 11
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 35
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 35
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DMGDH antibody is un-conjugated
    Application
    • 25
    • 21
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Cross-Reactivity
    Human
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from C-terminal of Human DMGDH.
    Isotype
    IgG
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  • Application Notes
    WB:1:500-1:3000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    DMGDH (Dimethylglycine Dehydrogenase (DMGDH))
    Alternative Name
    DMGDH (DMGDH Products)
    Synonyms
    MGC132281 antibody, DMGDHD antibody, ME2GLYDH antibody, Me2GlyDH antibody, 1200014D15Rik antibody, AI787269 antibody, dimethylglycine dehydrogenase antibody, dimethylglycine dehydrogenase L homeolog antibody, D-amino-acid oxidase antibody, Dimethylglycine dehydrogenase antibody, glycine cleavage system protein T antibody, dimethylglycine dehydrogenase precursor antibody, DMGDH antibody, dmgdh.L antibody, dmgdh antibody, SAR11_1253 antibody, EAMY_RS27375 antibody, EAMY_RS33570 antibody, VDBG_06516 antibody, Sinme_2570 antibody, HALXA_RS03495 antibody, Dmgdh antibody
    Background

    Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

    Binzak B.A., Mol. Genet. Metab. 69:181-187(2000).
    Binzak B.A., Am. J. Hum. Genet. 68:839-847(2001).
    Moolenaar S.H., Clin. Chem. 45:459-464(1999)

    Aliases: Dimethylglycine dehydrogenase antibody, Dimethylglycine dehydrogenase, mitochondrial antibody, Dmgdh antibody, M2GD_HUMAN antibody, ME2GLYDH antibody, mitochondrial antibody

    UniProt
    Q9UI17
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