CHRNA1 antibody (C-Term)

Catalog No. ABIN7180140

Product Details anti-CHRNA1 Antibody

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human CHRNA10.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Alternative Name: CHRNA1 (CHRNA1 Products)

Synonyms: CHRNA1 antibody, ACHRA antibody, ACHRD antibody, CHRNA antibody, CMS2A antibody, FCCMS antibody, SCCMS antibody, NACHRA1 antibody, AI385656 antibody, AI608266 antibody, Achr-1 antibody, Acra antibody, cholinergic receptor nicotinic alpha 1 subunit antibody, cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) antibody, CHRNA1 antibody, Chrna1 antibody

Background:

Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Sgard F., Mol. Pharmacol. 61:150-159(2002).
Lustig L.R., Genomics 73:272-283(2001).
Vandenberk I., Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.

Aliases: Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody, ACH10_HUMAN antibody, Alpha 10 nAChR antibody, Cholinergic receptor nicotinic alpha 10 antibody, Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody, Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody, CHRNA 10 antibody, CHRNA10 antibody, NACHR alpha 10 antibody, NACHR alpha-10 antibody, NACHRA10 antibody, Neuronal acetylcholine receptor protein subunit alpha 10 antibody, Neuronal acetylcholine receptor subunit alpha-10 antibody, Nicotinic acetylcholine receptor subunit alpha 10 antibody, Nicotinic acetylcholine receptor subunit alpha-10 antibody, OTTHUMP00000013620 antibody

UniProt: Q9GZZ6

Pathways: Skeletal Muscle Fiber Development