VAV1 antibody (Tyr174)
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- Target See all VAV1 Antibodies
- VAV1 (Vav 1 Oncogene (VAV1))
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Binding Specificity
- Tyr174
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VAV1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized non-phosphopeptide derived from Human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).
- Isotype
- IgG
- Top Product
- Discover our top product VAV1 Primary Antibody
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- Application Notes
- WB:1:500-1:3000, IHC:1:50-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- VAV1 (Vav 1 Oncogene (VAV1))
- Alternative Name
- VAV1 (VAV1 Products)
- Synonyms
- VAV antibody, Vav antibody, vav-T antibody, vav guanine nucleotide exchange factor 1 antibody, vav 1 oncogene antibody, vav guanine nucleotide exchange factor 1 L homeolog antibody, VAV1 antibody, Vav1 antibody, vav1.L antibody
- Background
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Background: Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Ana V. Miletic, J. Biol. Chem., Dec 2006, 281: 38257 - 38265.
Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003, 23: 6291 - 6299.
Vered Schapira, Cancer Res., Jun 2006, 66: 6183 - 6191.
Maya Groysman, J. Biol. Chem., Dec 2002, 277: 50121 - 50130.Aliases: Oncogene vav antibody, p95Vav antibody, Proto-oncogene vav antibody, Protooncogene vav antibody, VAV 1 antibody, VAV 1 oncogene antibody, VAV antibody, Vav proto oncogene antibody, VAV_HUMAN antibody, VAV1 antibody
- UniProt
- P15498
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
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