Mps1 antibody (Thr676)

Catalog No. ABIN7180102

Product Details anti-Mps1 Antibody

Target: Mps1 (TTK)

Binding Specificity: Thr676

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mps1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human TTK around the phosphorylation site of threonine 676 (D-T-T(p)-S-V).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Mps1

Target: Mps1 (TTK)

Alternative Name: TTK (TTK Products)

Synonyms: CT96 antibody, ESK antibody, MPH1 antibody, MPS1 antibody, MPS1L1 antibody, PYT antibody, AL022661 antibody, Esk1 antibody, Mps1 antibody, esk antibody, mps1 antibody, ncp antibody, Ttk protein kinase antibody, TTK protein kinase antibody, ttk protein kinase antibody, Ttk antibody, TTK antibody, ttk antibody

Background:

Background: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

Mills G.B., J. Biol. Chem. 267:16000-16006(1992).
Ota T., Nat. Genet. 36:40-45(2004).
Mungall A.J., Nature 425:805-811(2003)

Aliases: cancer/testis antigen 96 antibody, CT96 antibody, Dual specificity protein kinase TTK antibody, ECSTY kinase antibody, ESK antibody, FLJ38280 antibody, hMPS1 antibody, Monopolar Spindle 1 Like 1 antibody, MPH1 antibody, Mps 1 antibody, MPS1L1 antibody, Phosphotyrosine Picked Threonine Kinase antibody, Phosphotyrosine picked threonine-protein kinase antibody, PYT antibody, RP3-357D13.2 antibody, ttk antibody, TTK Protein Kinase antibody, TTK_HUMAN antibody

UniProt: P33981