IL2 Receptor beta antibody (Tyr364)

Catalog No. ABIN7180029

Product Details anti-IL2 Receptor beta Antibody

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Binding Specificity: Tyr364

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL2 Receptor beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human IL-2Rbeta/CD122 around the phosphorylation site of tyrosine 364 (Q-G-Y(p)-F-F).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Alternative Name: IL2RB (IL2RB Products)

Synonyms: IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody

Background:

Background: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

Hatakeyama M., Science 244:551-556(1989).
Dunham I., Nature 402:489-495(1999).
Mulloy J.C., J. Virol. 70:3599-3605(1996)

Aliases: CD122 antibody, CD122 antigen antibody, High affinity IL 2 receptor beta subunit antibody, High affinity IL 2 receptor subunit beta antibody, High affinity IL-2 receptor subunit beta antibody, IL-2 receptor subunit beta antibody, IL-2R subunit beta antibody, IL-2RB antibody, IL15RB antibody, IL2 receptor antibody, IL2RB antibody, IL2RB_HUMAN antibody, Interleukin 2 receptor beta antibody, Interleukin-2 receptor subunit beta antibody, P70 75 antibody, P70-75 antibody, P7075 antibody, p75 antibody

UniProt: P14784

Pathways: JAK-STAT Signaling, Growth Factor Binding