APLP2 antibody (Tyr755)

Catalog No. ABIN7179975

Product Details anti-APLP2 Antibody

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Binding Specificity: Tyr755

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human APLP2 around the phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Alternative Name: APLP2 (APLP2 Products)

Synonyms: HAI antibody, MT-SP1 antibody, MTSP1 antibody, PRSS14 antibody, SNC19 antibody, TADG15 antibody, TMPRSS14 antibody, APLP-2 antibody, APPH antibody, APPL2 antibody, CDEBP antibody, AI790698 antibody, Apph antibody, WALPLP2 antibody, aplp2 B antibody, APLP2 antibody, si:dkey-11k4.3 antibody, aplp2 A antibody, MGC86389 antibody, suppression of tumorigenicity 14 antibody, amyloid beta precursor like protein 2 antibody, amyloid beta (A4) precursor-like protein 2 antibody, amyloid beta (A4) precursor-like protein 2 S homeolog antibody, amyloid beta (A4) precursor-like protein 2 L homeolog antibody, ST14 antibody, APLP2 antibody, Aplp2 antibody, aplp2.S antibody, aplp2 antibody, aplp2.L antibody

Background:

Background: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts By similarity.

Sprecher C.A., Biochemistry 32:4481-4486(1993).
Wasco W., Nat. Genet. 5:95-99(1993).
von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).

Aliases: amyloid beta (A4) precursor like protein 2 antibody, Amyloid like protein 2 antibody, Amyloid precursor protein homolog HSD 2 antibody, amyloid precursor protein homolog HSD2 antibody, Amyloid protein homolog antibody, Amyloid-like protein 2 antibody, APLP-2 antibody, Aplp2 antibody, APLP2_HUMAN antibody, APPH antibody, APPL2 antibody, CDEBP antibody, CDEI box binding protein antibody, CDEI box-binding protein antibody

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour